Anion channelrhodopsins inhibit zebrafish behavior

Zebrafish embryos move spontaneously. In fish expressing anion channelrhodopsin, green light induces paralysis.
Video by @GadistiAisha pic.twitter.com/GhgxKbbpG5

— Adam Claridge-Chang (@adamcchang) July 5, 2017

Check out our recent preprint, a collaboration with the Jesuthasan group. We find that anion channelrhodopsins are effective inhibitors of zebrafish embryos, and that GtACR2 is not trafficked to the plasma membrane well.